What is Betadex Sulfobutyl Ether Sodium？

Betadex Sulfobutyl Ether Sodium refers to the sodium salt obtained via the alkylation reaction between Betadex and 1,4-butanesulfonic acid lactone under alkaline aqueous environments. As an anionic cyclodextrin derivative, it features outstanding water solubility compared with native Betadex. Betadex Sulfobutyl Ether Sodium is able to tightly bind to various drug molecules and form stable non-covalent inclusion complexes. This special inclusion effect brings multiple pharmaceutical advantages: it significantly improves the chemical stability and aqueous solubility of active pharmaceutical ingredients, elevates medication safety profiles, lowers renal toxicity risks, alleviates drug-induced hemolysis, accurately modulates the drug release rate, and effectively masks unpleasant odor and bitter taste of raw drugs.